THE EBNA3 FAMILY OF EPSTEIN-BARR VIRUS NUCLEAR PROTEINS ASSOCIATES WITH THE USP46/USP12 DEUBIQUITINATION COMPLEXES TO REGULATE LYMPHOBLASTOID CELL LINE GROWTH.

The Epstein-Barr virus (EBV) nuclear proteins EBNA3A, EBNA3B, and EBNA3C interact with the cell DNA binding protein RBPJ and regulate cell and viral genes.Repression of the Wine Racks CDKN2A tumor suppressor gene products p16(INK4A) and p14(ARF) by EBNA3A and EBNA3C is critical for EBV mediated transformation of resting B lymphocytes into immortali

Practical decision-making very often results in complex multiobjective optimization problems that can be solved only by advanced software.At present, it is available for singleobjective optimization and much less for multiobjective optimization.Therefore, the most common Monitors approach to multiobjective optimization is to reduce (scalarize) to i

Objectives.The aim of the work is to demonstrate the fundamental difference between fibre-reinforced foam concrete and traditionally-used wall materials in terms of tensile strength.Method.An analysis of the effectiveness of heat-insulating and structural fibre-reinforced concrete in terms of their mechanical and physical properties, including fros

The large amount of heavy metal chromium emissions from industrial production, ore smelting and sewage treatment plants have made chromium one of the most widespread heavy metal pollutants, with Cr (VI) being the most toxic.In recent years, people have gradually recognized the great harm of heavy metal chromium pollution, but the research on its pa